Strategically located in the heart of San Mateo with direct visibility from Highway 101, 610–616 South Amphlett Boulevard presents a rare opportunity to acquire a versatile mixed-use investment property with multiple income streams and long-term upside. Spanning two parcels totaling ±12,007 square feet, this asset includes a vacant ±3,700 SF automotive shop with a secured ±3,500 SF yard, a recently updated two-bedroom apartment, three storage units, and a four-bedroom single-family residence. A standout feature is the freeway-facing billboard, leased through July 2050, offering a stable and long-term income stream with annual CPI adjustments. The property’s C4 zoning supports a wide range of commercial uses, enhancing its redevelopment potential or continued operation as a multi-income investment. Located just minutes from Downtown San Mateo, the property benefits from proximity to Caltrain, San Mateo Japanese Garden, Shoreview Shopping Center, and San Francisco International Airport. With easy access to major thoroughfares including Highway 101, 280, and 92, the site is ideally positioned for both local and regional connectivity. Projected gross annual income is approximately $301,200, with market-rate rents across all units. This includes $9,500/month from the auto shop and yard, $3,700/month from the apartment, $4,400/month from the single-family residence, $6,000/month from the billboard lease, and $1,500/month from the storage units.