78 San Marcos Street is situated within the East Austin neighborhood near Rainey Street and Lady Bird Lake Trail. The surrounding area consists of retail, dining, and entertainment venues within a pedestrian-friendly environment. The site has neighborhood office zoning allowing multiple uses. It offers frontage along San Marcos Street and is accessible via East Cesar Chavez Street with proximity to Interstate 35 and Downtown Austin. Public utilities serve the property, and the immediate area includes mixed residential and commercial uses.