Own a cornerstone of Memphis history with the Historic Lowenstein Building, a true architectural gem positioned in the heart of the Memphis Medical District. Built between 1890 and 1891, this 10,611-square-foot property is a rare example of Italianate Queen Anne design, preserved for more than a century and listed on the National Register of Historic Places. The estate sits on a 0.40-acre site and offers stunning original details including ornate stained glass, intricate woodwork, grand staircases, soaring 12-foot ceilings, and seven fireplaces. The property’s storied past began as a private mansion and later served as a philanthropic hub and healthcare facility, carrying forward its legacy of significance. Today, it stands ready for a visionary buyer to reimagine its next chapter. With its prime location in a thriving hub near major hospitals, research centers, and Downtown Memphis, the site offers unmatched potential for adaptive reuse. Opportunities include conversion into a boutique hotel, luxury inn, event venue, executive office, corporate retreat, or mixed-use cultural destination that leverages the property’s historic character and architectural charm. Recent investment highlights include a $300,000 Tennessee Historic Development Grant awarded in 2024, bolstering redevelopment potential through historic tax incentives. Surrounded by ongoing economic growth in the Memphis Medical District and within easy reach of Downtown amenities, interstate connections, and the airport, this property provides a once-in-a-lifetime opportunity to combine heritage, functionality, and revenue potential in one remarkable address.