Marcus & Millichap is pleased to present 729 N Custer Avenue, a 21,249-square-foot medical office building (18,153 SF main floor plus 3,096 SF rentable basement) situated on a spacious 2.06-acre parcel in the heart of Grand Island’s established healthcare corridor. The property is located within the Medical Park Third Subdivision, surrounded by complementary medical and professional users that reinforce long-term tenant demand and patient traffic. This asset offers owner-users or investors a rare opportunity to acquire a large-format medical office building in a supply-constrained market where medical inventory of this scale is limited. The site’s generous acreage provides ample parking, efficient patient flow, and potential for future expansion or multi-tenant demising strategies. With strong visibility along N Custer Avenue, one of the area’s primary north–south arterials, the property benefits from excellent accessibility and proximity to regional amenities, including the Central Nebraska Regional Airport. The building’s placement in FEMA Flood Zone X further enhances its stability by minimizing insurance requirements and operating risk. Whether pursued as an owner-user opportunity, a value-add repositioning, or a long-term hold, 729 N Custer delivers a compelling combination of scale, location, and medical-use functionality that is increasingly difficult to replicate in the Grand Island market.