Now available: a 2,400 sq. ft. retail / commercial suite at 646 Highway 6 South, Houston, TX 77079, recently renovated in 2025. This property offers prime retail space for lease in Houston with excellent Highway 6 frontage, high traffic counts, and unmatched visibility in one of the city’s busiest commercial corridors. Located on the west side of Hwy 6, just south of Interstate 10 (I-10 Katy Freeway) and north of Memorial Drive, this property sits in a high-demand Houston retail corridor with strong demographics, heavy daily traffic, and a growing residential base. Businesses here benefit from superior exposure, a pylon sign opportunity, and easy access for both residents and commuters. The surrounding trade area features popular restaurants, including Lupe Tortilla, Blue Agave Cantina, and Ginger Thai Cuisine. The area is experiencing strong growth, with a new residential development and several recently built Houston apartment complexes along the Highway 6 corridor—driving even more daily foot traffic and consumer demand. This flexible commercial space for lease is ideal for a variety of uses, including: Automotive businesses: auto parts store, driving school, car glass repair, vehicle wrapping, or auto insurance office. Retail and service tenants: vape shop, flooring store, tile and granite supplier, hardware supply, door company, or showroom. With prime Houston retail space, heavy traffic exposure, and a location in the thriving Houston Energy Corridor / Memorial area, 646 Hwy 6 S is a premier choice for businesses looking to establish a strong presence in Houston’s retail real estate market.