6222 I-10 Office at 6222 I-10, San Antonio, TX 78201 offers a rare owner-user and investment opportunity with exceptional IH-10 frontage in San Antonio’s Northwest submarket. This freestanding 25,040 SF, two-story office building sits on 1.59 fenced acres and delivers outstanding visibility with both monument and dual billboard signage included. Renovated in 2020, the property combines immediate functionality with long-term value. Key upgrades include two, recently upgraded high-efficiency rooftop HVAC units, helping eliminate major near-term capital concerns. The building also features heavy 600-amp / 480Y/277V three-phase power, making it ideal for office, medical, educational, flex, assembly, and light industrial users under flexible I-1 zoning. Delivered vacant, the property gives buyers the advantage of immediate occupancy or repositioning potential. A secured parking field with 95 spaces, motorized entry gates, perimeter fencing, ADA compliance, and an elevator creates a controlled-access campus environment rarely found at this price point. Additional upside includes billboard rights and an existing communications tower for possible ancillary income opportunities. Positioned below replacement cost with direct interstate exposure, this is a standout acquisition for users and investors seeking visibility, flexibility, and scale.