415-938-8838
601-621 Portola Dr, San Francisco, CA for Rent

$34.08-$71.40 USD /SF/yr

Office/Medical, Office/Retail - For Rent
1/13
840-3,000 SF | 2 Spaces

601-621 Portola Dr
San Francisco, CA 94127
Miraloma


HIGHLIGHTS

  • Heavy Traffic Corner in Twin Peaks-Established Dental office of 27 years.

OVERVIEW

Prime Professional Medical/Wellness Office Space for Lease!! Position your business for long-term success in this fully built-out, highly visible professional space located in a prime, high-traffic corridor. Formerly home to a thriving dental practice for over 27 years, this well-designed and versatile property offers an exceptional opportunity for dental, medical, wellness, or select retail users seeking a turnkey or easily adaptable environment. Whether you are launching, expanding, or relocating, this space provides the infrastructure, visibility, and flexibility to support your growth—without the time and expense of building from the ground up. Property Features: Generous Layout: Approximately 3,000 sq. ft. of thoughtfully designed, functional space suitable for clinical, professional, or boutique commercial use. Built-Out Clinical Infrastructure Eight fully equipped operatories with plumbing, cabinetry, and fixtures already in place—ideal for dental use and readily adaptable for medical, wellness, or treatment-based services. Welcoming Reception Area: Spacious and comfortable waiting environment designed to enhance client and patient experience. Private Offices & Staff Areas: Dedicated administrative and provider offices, plus staff workspace and full kitchen/breakroom to support daily operations efficiently. Specialized Equipment & Treatment Areas: Includes digital X-ray system, sterilization room, and darkroom—convertible for medical imaging, lab, or procedural use depending on tenant needs. Restrooms: Modern, clean, and well-maintained facilities for patients, clients, and staff. Ample On-Site Parking: Convenient parking for both staff and visitors—an essential feature for healthcare and customer-facing businesses. Move-In Ready: Existing improvements allow for immediate occupancy, with flexibility for customization. Location Advantages: High-Visibility Setting: Prominent location with strong vehicle and foot traffic, providing excellent exposure for healthcare or retail-oriented businesses. Excellent Accessibility: Conveniently located near major transportation routes, residential neighborhoods, and established commercial services. Strong Community Demographics: Situated in a well-established area with consistent demand for healthcare, wellness, and neighborhood-serving retail services. Lease Highlights: Flexible Lease Terms Structured to accommodate a range of professional, medical, or retail users. Tenant Improvement Opportunities: Ability to customize layout and finishes to suit dental, medical, wellness, or boutique retail concepts. Immediate Occupancy Available: Minimal downtime—ideal for businesses seeking a seamless transition. Ideal Uses: This versatile space is well-suited for: Dental Practice (General or Specialty) Medical or Healthcare Office Wellness / Aesthetic / MedSpa Physical Therapy or Rehabilitation Specialty Medical Services Professional Office Use Boutique Health-Focused or Service Retail (subject to approval) Building Highlights Prime high-visibility location with strong exposure Former long-standing dental practice (27+ years) Turnkey clinical infrastructure with existing plumbing and wiring Flexible layout adaptable for medical, dental, wellness, or retail use Professional reception, private offices, and staff facilities On-site parking for convenience and accessibility Close proximity to major transportation corridors Zoning supports medical, professional, and related commercial uses Located in an established, high-demand service area Opportunity: This is a rare opportunity to secure a well-located, fully improved professional space with exceptional flexibility. Whether continuing as a dental office or transforming into a medical, wellness, or specialty retail destination, the foundation is already in place for long-term success. Contact us today to schedule a private tour and explore how this space can support your next phase of growth.

RENTAL DETAILS

SPACE AVAILABLE

840-3,000 SF

# OF SPACES

2

RENT RATE (MO)

$2.84-$5.95 USD /SF/mo

RENT RATE (YR)

$34.08-$71.40 USD /SF/yr

LEASE TYPE

Triple Net, Modified Gross

LEASE LENGTH

Negotiable

AVAILABLE

Now

BUILDING DETAILS

PROPERTY TYPE

Office

PROPERTY SUBTYPE

Office/Residential

TOTAL BUILDING SIZE

5,353 SF

BUILDING CLASS

B

YEAR BUILT

1990

PARKING SPACES

40

LAND DETAILS

LAND ACRES

0.27 AC

LAND SF

11,761.2 SF

ZONING

NC-1

ASK ABOUT THIS PROPERTY

Jules ClarkClark and Crooner Real Estate GroupMore Info
415-938-8838

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Jules ClarkClark and Crooner Real Estate GroupMore Info
415-938-8838

By clicking the button, you agree to Showcase's Terms of Use and Privacy Notice.