5520 Ruffin Road presents a rare opportunity to acquire a fully renovated, two-story office building in the heart of Kearny Mesa—one of San Diego’s most established and central business hubs. Situated on approximately 0.85 acres (37,026 SF) of land, the property features 17,210 square feet of highly improved office space with secure, on-site parking for 60 vehicles. Originally constructed in 1975 and extensively renovated in 2021, the building showcases modern finishes, upgraded HVAC systems, new roofing, landscaping, and elevator modernization—positioning it as a turnkey asset for an owner-user or investor. Offered at $6,700,000 ($389.31/SF), the property is held in fee simple and zoned IS-1-1, allowing for a range of commercial uses. Located in the Hazard Commercial Park submarket, the site offers excellent accessibility via I-15, I-805, and SR-52, and is just minutes from Montgomery-Gibbs Executive Airport. The surrounding area is home to major employers such as Qualcomm, General Atomics, and Sharp HealthCare, with robust demographic growth and a median household income exceeding $100,000 within a 3-mile radius. 5520 Ruffin Road is ideally suited for an office-based owner-user seeking a headquarters location or for an investor interested in a high-quality, centrally located asset with long-term potential in one of San Diego’s most vital employment corridors.