515 Spruce Street offers a rare opportunity to acquire a recently renovated boutique medical office building in the highly desirable Laurel Heights neighborhood of San Francisco. This single-tenant property is fully leased to the Regents of the University of California, operating as UCSF’s Department of Dermatology, ensuring long-term secure cash flow through December 31, 2031. The 4,403-square-foot building benefits from historical significance and functional upgrades, including a recent renovation with seismic improvements. Positioned in a mission-critical location for UCSF, the tenant has maintained presence for 40 years, demonstrating strong commitment to the site. Beyond its medical specialization, the property enjoys excellent commuter accessibility, surrounded by affluent demographics and near Laurel Village retail amenities. With consistent occupancy by an investment-grade tenant, historic identity, and neighborhood infill positioning, 515 Spruce Street presents a compelling long-term investment opportunity in one of San Francisco’s most stable and prestigious medical office markets.