Exceptional opportunity to lease a highly improved freestanding building of 56,159 square feet in the most strategic location in all of San Diego, located in the heart of Kearny Mesa. Providing exceptional freeway and surface street access, this facility logistically from a business and quality of life perspective, is a home run. 4650 Overland Avenue is perfect for any flex, R&D, life science, lab, medical, and precision manufacturing applications. The interior has a mix of lab space, clean rooms, conference, private offices, open-plan bullpen areas, kitchen/lunchroom/lounge section, patios, and skylights. The warehouse space has numerous dock loading doors, great clear height, locker rooms, and showers. With a very distinctive architecture, this property creates an exceptional client and employee experience and energy that is unique and in a class of its own. All of this is supported by a robust HVAC and distribution system, multiple floor drains, waterlines, fully sprinklered areas, a backup diesel generator, a significant gas and air network, and a 4,000-amp, 277/480-volt power capacity, which can be cost-effectively expanded due to prior infrastructure preparation. The entire property can easily be enclosed, and a conduit is in place to install security gates. 4650 Overland Avenue is situated within the Spectrum Center, a very walkable and upscale neighborhood with a significant array of amenities within minutes. Multiple throughfares are proximate to the facility, including Interstates 15, 8, and 805, as well as the 163 and 52 freeways, which route into San Diego within a 5-minute drive and extend into the Inland Empire and Los Angeles in under two hours. For easy connections to international and domestic markets, the San Diego International Airport is only 9.2 miles away. Don't miss out on a one-of-a-kind facility that can serve any manufacturing or distribution business long into the future, offering critical in-place infrastructure and flexible interior configurations that allow a business to scale and grow with its evolving operational requirements. This opportunity is perfect for an owner/user who is looking to expand their operation into a showstopping space.