4494 Mission Street presents a rare opportunity to acquire a historic commercial property in San Francisco’s vibrant Excelsior District. Formerly home to the iconic Central Drug Store for over a century, this ±2,495-square-foot building offers exceptional street frontage and visibility at the corner of Mission Street and Santa Rosa Avenue. The property includes two garages with access from Santa Rosa Avenue, providing valuable on-site parking and storage. The open floor plan features approximately 1,300 square feet on the ground level plus a ±525-square-foot mezzanine, offering flexibility for retail, office, or creative use. The existing dropped ceiling can be removed to maximize ceiling height and natural light from south-facing windows.