Positioned in the heart of Philadelphia’s Spruce Hill Historic District, the East Building at 4147 Woodland Avenue offers a rare opportunity to own a piece of institutional heritage with modern upgrades. Originally constructed in 1900 and thoughtfully renovated in 2006, this two-story masonry structure blends historic charm with contemporary functionality. The building previously served as the Department of Humanities for Saint Joseph’s University, underscoring its suitability for academic, civic, or professional office use. The property occupies a corner lot with dual frontage on Woodland Avenue and South 42nd Street, enhancing visibility and accessibility. Its location is exceptionally transit-friendly, with over ten bus stops within two blocks and close proximity to the 40th Street Trolley, offering seamless regional connectivity. The surrounding Spruce Hill neighborhood is celebrated for its Victorian-era architecture and vibrant community character, recently recognized by the Philadelphia Historical Commission. With CMX-1 zoning, the site supports a variety of low-impact commercial uses, including professional offices, medical practices, and institutional functions. The building’s 13.5-foot ceiling heights, concrete floors, and stucco exterior provide a solid foundation for adaptive reuse or continued office operations. This is a compelling opportunity for investors or owner-users seeking a historically significant, well-located asset in one of West Philadelphia’s most architecturally rich districts.