410 SE Main St in Simpsonville, SC is a fully vacant commercial building that was previously used as a residential property. The asset presents a value-add opportunity and is well positioned for renovation and conversion to a commercial use. Ideal for professional office, medical, or live/work use, allowing an owner-user to renovate and occupy while benefiting from long-term flexibility and future upside. Positioned along S Main Street in Simpsonville, SC, this ±0.77-acre property offers a rare opportunity to acquire a highly visible site within a growing commercial corridor. Zoned ROI (Residential Office Institutional), the property supports a variety of uses including professional office, medical, live/work, or boutique business operations. The site features an existing ±1,522 SF residence and a ±800 SF secondary structure, providing immediate usability with the ability to renovate, occupy, or adapt to a range of business needs. With approximately 106 feet of road frontage, the property benefits from strong exposure and accessibility, making it well-suited for users seeking a Main Street presence with flexible use options.