Blocks from Downtown St. Petersburg and adjacent to St. Anthony’s Hospital, 400 15th Street N presents a fully renovated medical office property in one of the city’s most active healthcare corridors. Having undergone a comprehensive renovation from top to bottom, including upgraded electrical systems, new cabinetry and counters, and modern HVAC improvements, it creates a professional and comfortable environment tailored for clinical operations.
Ideal for medical, retail, or professional use, the interior layout features a series of private offices, exam rooms, and break areas that support various healthcare functions. The property’s CCS-2 zoning permits a diverse range of commercial and medical uses, providing flexibility for future ownership or occupancy strategies.
Great Fit for:
Primary care
Community health clinics
Federally Qualified Health Centers (FQHCs)
Infectious disease clinics
Chronic care (diabetes, HIV, wound care)
Behavioral Health / Mental Health Providers
Social services
Veteran services
Housing authority offices
Counseling centers
Psychiatry
Substance use treatment (outpatient)
Case management
Two adjacent vacant lots provide significant value-add potential. One lot has been graveled for immediate parking use, while the second offers the opportunity for fencing or specialized outdoor space, ideal for veterinary or wellness practices. The location benefits from strong visibility and accessibility, with proximity to major thoroughfares, including Interstates 375 and 275, public transit, and walkable downtown amenities.
With its strategic location, modernized infrastructure, and value-add optionality, 400 15th Street N is well-positioned for long-term value in St. Petersburg’s growing medical and professional services market.