Positioned in the heart of Charlottesville’s highly desirable Pantops submarket, 384 Worrell Drive presents a rare opportunity to acquire or redevelop a 5.48-acre site with an existing 10,371-square-foot historic office building. The property is nestled within the park-like setting of Peter Jefferson Place, offering scenic views, walking trails, and a tranquil environment that enhances its appeal for professional, medical, or mixed-use development. With minimal topography and dual access points, the site is ideally suited for redevelopment or adaptive reuse. Its proximity to Sentara Martha Jefferson Hospital and the Peter Jefferson Place Office Park adds strategic value for healthcare, office, or retail users. Zoned PD-MC (Mixed Commercial), the property benefits from flexible entitlements, and the underlying County Comprehensive Plan supports a wide range of uses. Whether preserved as a character-rich office building or transformed into a modern mixed-use destination, 384 Worrell Drive offers investors and developers a compelling canvas in one of Charlottesville’s most vibrant growth corridors.