Office Space for Lease in East Village – 345 15th Street, San Diego, CA 92101 Discover a prime office opportunity in the heart of San Diego’s vibrant East Village. Located at 345 15th Street, this versatile office space offers ±2,500 to 5,000 SF available for lease at $2.00/SF + utilities. Ideal Location Situated just blocks from I-5 and Hwy 163, this office space offers excellent freeway access and walkability to premier local amenities. Enjoy proximity to: Petco Park Mission Brewery Fault Line Park Convention Center Popular cafes and eateries like Basic Pizza, Copa Vida Coffee, and The Mission Café