Positioned in the heart of Midtown Manhattan, 340 Madison Avenue offers a premier HQ leasing opportunity with a tower block of up to 463,750 rentable square feet, a base block of up to 139,635 rentable square feet, and boutique office suites from approximately 5,000 square feet. Dupped 340MAD, this 22-story, 760,000-square-foot office property commands a full-block presence between 43rd and 44th Streets, combining historic character with modern performance. This Class A building offers efficient 30,000- to 40,000-square-foot floor plates, largely configured in open-plan layouts, with options ranging from boutique pre-builds to large-scale headquarters opportunities. Tenants benefit from standout branding potential, including private lobby entrances, exclusive outdoor spaces, and the ability to create a dramatic two-floor atrium. A recently completed 10,000-square-foot tenant amenity center, accessible from all floors, features conferencing facilities, event spaces, private study rooms, lounges, meditation areas, and travel showers. The 2020-renovated lobby elevates arrival with 18-foot ceilings, curated finishes, and modernized elevator systems, reinforcing a best-in-class workplace experience within a LEED Gold and ENERGY STAR-certified asset. This offering delivers a rare combination of scale, flexibility, and prestige in one of Manhattan’s most recognizable office corridors. Situated directly across from Grand Central Terminal, 340 Madison provides unmatched access to New York City’s transit infrastructure, enabling seamless connectivity via major subway lines, Metro-North trains, local and express buses, and Citi Bike hubs, all within a two-minute desk-to-train commute. The surrounding environment enhances daily productivity and employee experience, with Bryant Park and the New York Public Library just steps away, offering green space, programming, and cultural appeal. The immediate area features an exceptional concentration of dining, hospitality, and retail options, alongside proximity to the Theatre District and Rockefeller Center. This connectivity places tenants at the nexus of Midtown’s business ecosystem, allowing teams to move effortlessly across the city while benefiting from a vibrant, amenity-rich environment. Located within the highly coveted Grand Central submarket, 340 Madison Avenue positions tenants among global industry leaders, including JPMorgan Chase, Amazon, and MetLife, fostering collaboration, visibility, and access to top-tier talent. The neighborhood blends historic significance with modern commercial energy, supporting a dynamic workforce drawn to convenience, prestige, and lifestyle offerings. 340 Madison Avenue delivers a compelling headquarters or growth opportunity designed to support evolving business needs while elevating employee engagement and corporate identity.