Newport Irvine Medical Center 3300 Irvine Avenue, Newport Beach, CA 92660 Premier practices warrant premiere real estate. The Newport Irvine Medical Center is poised to emerge as one of Orange County’s leading medical office buildings. This state-of-the-art facility has been meticulously designed to meet the expectations of the area’s affluent consumer groups, offering a unique and superior experience for both patients and medical professionals. The building is being transformed to offer a rare opportunity to lease new Class A construction, including large medical office spaces, in the highly sought-after Newport Beach submarket. Newport Irvine Medical Center welcomes a range of users from solo providers and large group practices, to new ambulatory surgery and imaging centers.