Welcome to 323 James St, an excellent commercial leasing opportunity in the heart of downtown Syracuse. This versatile building offers three floors of office space, each approximately 6,000 sq ft, available together or individually. The space is divided into large rooms/offices, ideal for a variety of professional uses including corporate offices, medical/health services, educational programs, nonprofits, government agencies, call centers, and community organizations. Property Features: Up to 18,000 sq ft total 6,000 sq ft per floor Lease full building or one/two floors Multiple large private rooms — flexible layout Men’s & Women’s restrooms on every level Elevator access On-site parking lot directly across the street Professional location in Syracuse business district Immediate availability Situated on James Street, one of Syracuse’s established commercial corridors, providing easy access to downtown, highways, and public transportation.