The Enterprise Building at 320 North E Street is an architecturally prominent five-story landmark building in downtown San Bernardino. This building offers a range of small offices, executive suites, and large office spaces for rent. Additionally, there are many flagship retail storefronts and corporate or private event spaces available. This is an invitation to join the Enterprise today. Designed in 1927 by famed local architect Howard E. Jones in the Modern Classical style for The Andreson Co., led by civic leader John Andreson Jr. and his brother, William. The structure is a contributing building to the historic value of Downtown San Bernardino, and is the only landmark office tower in the Inland Empire Region of Southern California. Since its opening in 1927, the building has undergone numerous changes and renovations, attracting some of San Bernardino’s most influential companies, including the city's first Bank of America branch. The land on which the building stands is also historically significant, as it is the site of San Bernardino's first brewery and the location where the Inland Empire was originally conceived by entrepreneurial pioneer John Anderson in 1871. The building has remarkably retained its character and original luster, and the current ownership has modernized many of the building's systems to provide modern-day comfort in this prime historic gem. Built as the largest mixed-use office building in the city, The Enterprise Building continues to be an inspiration for progress. The ownership and property management team are contemporary pioneers in restoration and revitalization efforts in downtown San Bernardino, hosting many of downtown’s lively businesses and events. Are you ready to build your enterprise? The Historic Enterprise Building Team looks forward to speaking with interested parties about leasing a brand-new office suite.