Cushman & Wakefield is pleased to present a rare value-add investment opportunity at 2761–2765 16th Street, a 17,170± square-foot mixed-use property located in the heart of San Francisco’s vibrant A.I. and technology corridor. Originally built in 1929, the building underwent a comprehensive renovation in 2022, including a full seismic and structural retrofit, upgraded building systems (HVAC, 800-amp power, utilities, sprinklers), ADA-compliant restrooms and entrances, and a new roof. The property is divided into two condominiums and features a gated loading and delivery area with rear access via Enterprise Street.
2765 16th Street (12,046± sq. ft.) is fully leased to DaVita (NYSE: DVA) with 12-year remaining lease term with 10% rent increases every 5 years. 2761 16th Street (5,124± sq. ft.) offers a compelling value-add opportunity, with a planned vacancy in March 2026 and the potential to achieve a stabilized return on cost of 9.50%+.
2761–2765 16th Street is a centrally located mixed-use property in San Francisco’s Mission District, positioned along the high-traffic 16th Street corridor (25,400+ vehicles daily) between Folsom and Harrison Streets. The area is a rapidly growing hub for Generative A.I., Life Sciences, and Technology, with neighbors such as Sequoia, OpenAI, Euclid AI, DoorDash, Comcast, Thinking Machines and Ouster, to name a few. The property offers exceptional accessibility with immediate proximity to the 16th & Mission BART station, multiple Muni routes, and easy freeway access.
Surrounded by popular retail, dining, and entertainment options—plus national brands like Target, Costco, and Whole Foods—the site is minutes from the Financial District, SoMa, Hayes Valley, and Chase Center. Nearby medical centers, including UCSF Mission Bay, Zuckerberg SF General, and Sutter CPMC, support DaVita’s strong tenancy. The area features outstanding demographics, with average household income over $212,300 within one mile and a population exceeding 577,000 within three miles.