143 Fulton Street is in the Financial District of Manhattan, near the intersection of Fulton Street and Nassau Street. The property is situated on a block with mixed commercial uses and is adjacent to a major hotel. Public transit access is present via the Fulton Street Transit Center, which connects multiple subway lines and the PATH system. Nearby landmarks include the Oculus Transportation Hub, One World Trade Center, and Zuccotti Park. The surrounding area contains retail, dining, hospitality, and office buildings