Introducing an exceptional commercial opportunity along US-41 (Tamiami Trail) in the heart of Port Charlotte’s primary business corridor. This 1.1-acre Commercial General (CG) property combines outstanding visibility, flexible development characteristics, and highly sought-after access in one of the county’s most active commercial submarkets. The property features a 5,145 SF freestanding commercial building positioned on approximately 0.36 acres, with the remaining 0.74 acres of vacant CG-zoned land offering significant expansion or redevelopment potential. Currently configured as a single combined unit (originally Units 101–103), the building is tenant-occupied by an event venue on a short-term lease, providing the next owner substantial flexibility for owner occupancy, re-tenanting, or pursuing a new commercial development concept. While the building is currently condominiumized, new ownership has full authority to collapse the condo association should they desire to do so. Situated within Charlotte County’s Commercial Overlay District, the property benefits from a Floor Area Ratio (FAR) of 1.2 and allowable building height up to 60 feet, giving owners the latitude to design larger-scale retail, office, medical, or mixed-use concepts. The site’s development profile is further enhanced by Flood Zone X designation, reducing complexity and insurance costs for future improvements. The property delivers premier exposure and access with direct frontage along US-41 (61,000 VPD) and additional access via Ellicott Circle NW, which provides a connection to the signalized intersection at US-41 & Midway Blvd (79,700 VPD). This dual-access configuration creates optimal ingress/egress and visibility for a wide range of commercial users. The building itself has undergone notable structural and wind-mitigation improvements, including a refurbished metal roof and reinforced 3-Point truss connections tied directly into concrete block pillars—an investment that enhances its long-term durability. Positioned less than five miles away from the 785-room Sunseeker Resort, now under Blackstone Real Estate ownership and rebranded as a Hilton Curio Collection, the property is well-located to benefit from continued economic growth, increasing tourism volume, and the strengthening commercial landscape along the US-41 corridor. With flexible zoning, substantial vacant land, strong traffic counts, and a highly visible frontage location, 2421–2423 Tamiami Trail presents a rare opportunity for investors, developers, and owner-users seeking a high-exposure site with meaningful upside potential in a rapidly growing market.