168 Centre Street is a premier Commercial & Medical Office Building that is located at the vibrant intersection of SoHo, Chinatown, and Little Italy. 168 Centre is a boutique 5-story commercial building engineered for high-volume clinical practices, ambulatory facilities, and professional office suites. Building Highlights & Features: Renovated Main Lobby: A newly updated, contemporary lobby creates an inviting, professional entrance for patients, clients, and staff. Double Elevator Service: Equipped with dual passenger elevators to ensure efficient vertical transport and seamless access across all floors. Flexible Layouts: ~7,000 SF floor plates accommodate custom medical buildouts, private exam rooms, diagnostic suites, or modern open-plan administrative offices. Prime Transit Connectivity: Situated steps from the Canal Street transit hub, delivering immediate access to the 6, N, Q, R, W, J, and Z subway lines. Established Tenant Ecosystem: The property serves as a recognized Downtown healthcare destination, anchored by premier medical networks and specialized outpatient providers such as Mount Sinai Doctors: Features comprehensive multi-specialty care suites, including Mount Sinai oncology, surgery, hepatology, and cardiology departments. SoHo Ambulatory Surgical Center (SoHo ASC): A state-of-the-art outpatient facility supporting specialized surgical procedures and gastroenterology care. Rendr & Clinical Groups: Houses independent medical practices designed to deliver accessible, multilingual healthcare tailored to the Lower Manhattan community.