Presenting a rare opportunity to lease up to 29,654 square feet of prime commercial space in the heart of Los Angeles’ iconic Fashion District. Located at 221 East 12th Street, this contemporary corner building sits at the nexus of Santee Alley, a vibrant hub for fashion, retail, and culture, offering unmatched visibility and exposure between two signalized intersections. The property is ideal for boutique retail concepts, creative studios, salons, galleries, professional offices, or restaurant ventures seeking to thrive in a high-traffic, affluent area. This dynamic mixed-use space features expansive storefronts with abundant natural light, modern industrial finishes, and full 24/7 access. Tenants benefit from premium signage opportunities, additional storage availability, and proximity to multiple major thoroughfares. The location is less than 30 minutes from both the Los Angeles International Airport and the Bob Hope Airport, ensuring regional and national connectivity. 221 East 12th Street is also in proximity to many major tourist locations like Crypto.com Arena, formerly known as the Staples Center, home to the Los Angeles Lakers, the Los Angeles Convention Center, and the GRAMMY museum, drawing in additional foot traffic to the area. Positioned in one of LA’s most sought-after neighborhoods, the property enjoys direct access to the city’s ever-expanding public transportation network, including commuter rail and transit lines. With over 1,200,000 people in a 5-mile radius and total consumer spending exceeding $10.8 million, this location offers unparalleled access to a qualified customer base and workforce. The site is exposed to more than 11,000 vehicles per day, maximizing brand visibility and foot traffic. Downtown Los Angeles continues to attract tenants due to its proximity to clients, infrastructure, and ability to draw talent from across the region. The Fashion District itself spans over 100 blocks and is globally recognized as a center for fashion, textiles, and design. Businesses here benefit from a dynamic ecosystem of high-end showrooms, wholesale apparel vendors, and cutting-edge design studios. Whether launching a flagship retail store, establishing a creative headquarters, or opening a destination restaurant, 221 East 12th Street offers flexibility, exposure, and location to elevate a brand in one of Los Angeles' most energetic and influential districts.