2205 52nd St S consists of two vacant parcels (Lots 2 & 3) totaling 0.37 acres with 90-foot frontage and 180-foot depth, zoned CL-2. Permitted uses include retail, professional/business offices, personal services, restaurants, car washes, churches, funeral homes, and more. Setbacks are 10 feet front, 6 feet side, and 0 feet rear from the alleyway, maximizing the buildable area. The property sits two blocks off 22nd Ave S, a high-traffic corridor that provides steady and consistent traffic, along with excellent visibility for any commercial use. Gulfport’s downtown, waterfront, and amenities are minutes away, with easy access to St. Petersburg, I-275, and the beaches. The property is not located in a flood zone — no flood insurance requirement — and public water and sewer are available nearby. This property is perfect for a future office space, retail building, or single family home!