Positioned in Columbia’s premier healthcare corridor, 200 N. Keene Street offers an exceptional opportunity to acquire a high-quality medical office building in a thriving regional market. This 26,265-square-foot, two-story facility is situated on 1.24 acres with superior visibility along North Keene Street, the city’s primary medical district. The property’s institutional-grade construction and meticulous maintenance make it an ideal choice for healthcare systems, medical groups, and professional office users seeking a flagship location. The building features 47 private offices, 8 conference rooms, 10 restrooms, and kitchenettes on each level, complemented by elevator access for multi-story convenience. Its strategic location ensures proximity to major hospitals and healthcare providers, while excellent signage opportunities and high traffic counts enhance brand exposure. The M-OF zoning provides flexibility for a wide range of medical and professional uses, creating strong potential for owner-occupancy or value-add investment strategies. Offered at $5,120,000 ($195/SF), this asset represents a rare chance to secure a property in Columbia’s most sought-after medical district. For investors seeking scale, an adjacent property at 205 Portland Street is available for portfolio acquisition, enabling campus-style development and operational efficiencies. With strong demographics, robust daytime employment, and easy access to Interstate 70, this property is positioned for long-term success.