Position your business in one of Chicago's most dynamic mixed-use corridors at 1528 W. Taylor Street. Located in the heart of the Illinois Medical District and adjacent to the historic Little Italy neighborhood, the property benefits from a dense residential population, a substantial daytime workforce, and consistent traffic generated by nearby medical, educational, and commercial destinations. The location provides convenient access to downtown Chicago, I-290, CTA bus routes, and the Blue Line, making it easily accessible for employees, customers, and patients. Ideal for retail, restaurant, medical, office, wellness, or service-oriented users seeking a highly connected urban location. Listing Highlights. Current tenant will be vacating 7/31/2026. Available as is or can deliver as vanilla box.