DOWNTOWN MESA | UNIQUELY LOCAL As the upcoming urban redevelopment center in the Phoenix-Mesa metro area; opportunities abound to redevelop property and grow a business in downtown Mesa. Nestled in the heart of the third largest city in Arizona, Mesa is home to the technologies of tomorrow and one of Arizona’s oldest and largest historic commercial districts. With business incentives such as the Downtown Sign Program, the development of the Innovation District plus a dedicated Downtown Transformation Office—Downtown Mesa is the vibrant destination.