707-690-5295
1250 Main St, Napa, CA for Rent

Office, Office/Medical, Retail - For Rent
1/11
938-13,809 SF | 6 Spaces

1250 Main St
Napa, CA 94559
Central Napa


HIGHLIGHTS

  • Class A Building in Napa, Wine & Culinary Capital of the World
  • Ideal Location for AgTech, MedTech, CleanTech & Professional Service Businesses
  • Global Wine Production Hub, Leveraging Regional Prestige
  • High Visibility & Thriving Local Economy for Strategic Growth
  • Access to Skilled Workforce in Hospitality, Wine, Food, and Tech
  • 4,000 to 20,000 sq ft of office and medical space in Napa Innovation Center

OVERVIEW

Napa Innovation Center, located at 1250 Main Street in downtown Napa, CA is a Class A office building offering approximately 50,000 square feet of professional space designed for modern business needs. With its striking architecture and prominent corner presence at Main and Clinton Streets, this three-story building delivers both visibility and prestige in one of Napa’s most walkable and dynamic commercial districts. Surrounded by top-tier restaurants, boutique retail, luxury hotels, and cultural destinations, the property boasts a Walk Score of 97—placing tenants at the center of it all. The building features a variety of fully built-out suites ranging from private offices to expansive, full-floor layouts, allowing businesses to scale and customize as needed. Inside, tenants are welcomed by elegant stone lobby flooring, high-end finishes, and abundant natural light through double-pane, tinted glass windows. Each floor is served by elevator access and includes well-appointed restrooms, creating a professional and comfortable environment for staff and guests alike. With modern energy management systems, high-speed data connectivity, and keyless after-hours access, Napa Innovation Center is built to meet the demands of today’s high-performance teams. Parking is available with 30 surface spaces offered at an affordable monthly rate—an invaluable asset in Napa’s bustling downtown. Beyond its physical features, the property offers a strategic advantage as part of Napa’s thriving business ecosystem. Known globally for its wine industry, culture, and culinary excellence, the region also supports a growing network of companies in technology, healthcare, design, and professional services. Its central location provides convenient access to major transportation routes and is within one hour of three international airports, offering seamless local and international connectivity. For companies seeking a prestigious address that balances form and function in one of Northern California’s most iconic destinations, Napa Innovation Center at 1250 Main Street delivers a rare and compelling opportunity to thrive in the heart of downtown Napa.

RENTAL DETAILS

SPACE AVAILABLE

938-13,809 SF

# OF SPACES

6

RENT RATE (MO)

Request Info for Rent

RENT RATE (YR)

Request Info for Rent

LEASE TYPE

Triple Net, Negotiable, TBD, Full Service Gross

LEASE LENGTH

Negotiable

AVAILABLE

Jan 01, 2026

BUILDING DETAILS

PROPERTY TYPE

Office

PROPERTY SUBTYPE

Medical

TOTAL BUILDING SIZE

45,455 SF

BUILDING CLASS

A

YEAR BUILT

2008

PARKING SPACES

30

LAND DETAILS

LAND ACRES

0.33 AC

LAND SF

14,375 SF

ZONING

DMU

ASK ABOUT THIS PROPERTY

Zen Hunter-IshikawaWiseman Commercial, Inc.More Info
707-690-5295

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Zen Hunter-IshikawaWiseman Commercial, Inc.More Info
707-690-5295

By clicking the button, you agree to Showcase's Terms of Use and Privacy Policy.