This three-story commercial property in Tampa Heights offers a rare opportunity for owner-users or investors seeking a high-visibility location in one of Tampa’s fastest-growing corridors. Originally constructed in 1910 and fully renovated in 2015, the ±3,350 SF building combines historic architectural character with modern upgrades, creating a distinctive and functional space. The layout features an open first floor ideal for reception or collaborative work areas, while the upper levels provide private offices and suites. The second floor includes a suite with a luxury en-suite and balcony overlooking Downtown Tampa, and the third floor offers a suite with a full bathroom, making it suitable for executive offices or optional live-work use. The property includes a paved driveway for parking along the west side and additional parking via an alley on the east side. Zoned CG (General Commercial) with a future land use designation supporting mixed-use urban development, this asset offers flexibility for professional offices, creative studios, or multi-tenant configurations. Strategically positioned within Tampa Heights, the property is surrounded by significant public and private investment and lies within one of Tampa’s most active redevelopment corridors. Nearby transformative projects include Gas Worx, which is reconnecting Downtown Tampa and Ybor City, as well as the planned East Ybor redevelopment led by Darryl Shaw, expected to include a future campus for Tampa General Hospital. Additionally, a nearby property just south of the subject site has proposed plans for a mixed-use development featuring ground-floor retail storefronts with over 250 residential units above, adding significant density and further reinforcing the continued growth of the corridor. Just minutes from Downtown Tampa, Armature Works, and the Tampa Riverwalk, and within an Opportunity Zone, this property provides significant tax incentive potential and long-term value in a thriving redevelopment area. With high visibility, flexible office layout, on-site parking, and proximity to major redevelopment projects, 105 W Columbus Drive represents a compelling opportunity for both owner-users and investors seeking a presence in one of Tampa’s most dynamic urban growth corridors.