100 S Main Street presents an opportunity to acquire a purpose-built Class A medical office asset in the heart of Smyrna, Delaware. Situated on a 3.14-acre campus, the three-story property contains approximately 113,000 square feet and is reported to be 74% leased by regional healthcare tenants. The asset benefits from an established healthcare-oriented tenancy profile and a professionally managed campus environment designed to support long-term medical and office use. The property's location strengthens its appeal as a regional healthcare destination. Positioned approximately two blocks from Dupont Boulevard (U.S. Route 13) and within one mile of the Delaware Route 1 interchange, the building offers convenient access to both northern and southern Delaware. Smyrna's location between Wilmington and Dover supports access to a broad patient base, workforce population, and surrounding communities. The property is also recognized as part of Smyrna's established medical district, creating proximity to complementary healthcare services and providers. The combination of existing occupancy, institutional-quality construction, regional accessibility, and healthcare-focused positioning provides investors with an asset that serves a critical community function while benefiting from Delaware's central transportation network. Its campus setting, parking availability, and visibility along a well-established commercial corridor further contribute to its long-term relevance for healthcare and professional office users.